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GSD_003HZMN.1

USA/GSD_003HZMN.1/2026-07-03
M. Kirby, R. Garten, T. Davis & V. Dugan

Centers for Disease Control and Prevention, Influenza Division

Submission details

Submission ID
PZ985832.1.seg1/PZ985834.1.seg2/PZ985831.1.seg3/PZ985837.1.seg4/PZ985836.1.seg5/PZ985835.1.seg6/PZ985830.1.seg7/PZ985833.1.seg8
Submitting group
Date submitted
2026-09-16 07:48:02 UTC
Date released
2026-09-16 08:39:22 UTC

INSDC

bioprojectAccession
INSDC accession seg1
INSDC accession seg2
INSDC accession seg3
INSDC accession seg4
INSDC accession seg5
INSDC accession seg6
INSDC accession seg7
INSDC accession seg8
NCBI release date
2026-09-11

Clade

Clade HA
D.3.1
Clade NA
D.2

Sample details

Collection country
USA
Collection subdivision level 1
Pennsylvania
Collection date
2026-07-03
Isolate name
A/Pennsylvania/120/2026

INSDC seg4

subtype_seg4
H1

INSDC seg6

subtype_seg6
N1

Alignment and QC

Length seg1
2316 (99.9%)
Total ambiguous nucs seg1
3
Total inserted nucs seg1
36
Total SNPs seg1
83
Length seg2
2316 (100%)
Total inserted nucs seg2
42
Total SNPs seg2
71
Length seg3
2208 (100%)
Total inserted nucs seg3
57
Total SNPs seg3
83
Length seg4
1752 (100%)
Total SNPs seg4
110
Length seg5
1540 (100%)
Total inserted nucs seg5
43
Total SNPs seg5
62
Length seg6
1434 (100%)
Total inserted nucs seg6
1
Total SNPs seg6
23
Length seg7
1002 (100%)
Total inserted nucs seg7
20
Total SNPs seg7
23
Length seg8
865 (98.6%)
Total inserted nucs seg8
14
Total SNPs seg8
39

Nucleotide mutations

Mutations called relative to the NC_026438.1, NC_026435.1, NC_026437.1, CY121680.1, NC_026436.1, MW626056.1, NC_026431.1 & NC_026432.1 references

Substitutions

seg1

  • A18G
  • A90C
  • A96G
  • A108G
  • A132G
  • A138G
  • G161A
  • A174G
  • G198A
  • T201C
  • A225G
  • C242T
  • A243G
  • C285A
  • A291G
  • C309T
  • G375A
  • A441G

seg2

  • G42A
  • C114T
  • A138G
  • A159G
  • G168A
  • G180A
  • C192T
  • T207A
  • T210C
  • T222C
  • G225A
  • C297T
  • G312A
  • A345G
  • A366G
  • T384C
  • T397C
  • G414A

seg3

  • G40A
  • R53A
  • T81C
  • G84C
  • A88G
  • C90T
  • C99T
  • A114T
  • G126A
  • C153T
  • C162T
  • C165T
  • G187A
  • G204A
  • G298A
  • G423A
  • G477A
  • G498A

seg4

  • A30G
  • C42A
  • A47G
  • G57A
  • A119G
  • T161C
  • C164T
  • G188A
  • A231C
  • C293G
  • C318T
  • G322A
  • G360A
  • A408C
  • G416A
  • A429G
  • C443T
  • A456G

seg5

  • A33G
  • G42T
  • C87T
  • A97G
  • C141A
  • A162G
  • C171T
  • T177C
  • C180T
  • C249A
  • A288C
  • G298A
  • G309A
  • T314C
  • G315A
  • R341A
  • T365A
  • A390G

seg6

  • T50C
  • A144G
  • G163A
  • C452A
  • G607A
  • G611A
  • A785G
  • T799C
  • A818G
  • C893T
  • G914T
  • T1016C
  • A1049G
  • A1091G
  • C1108T
  • C1187T
  • A1193G
  • A1196G

seg7

  • G75A
  • C124A
  • G238A
  • G258A
  • A293G
  • G306A
  • G339A
  • C375A
  • T432C
  • G441T
  • G492A
  • C507A
  • G600A
  • C622A
  • G660A
  • T663C
  • G687A
  • A689G

seg8

  • C6A
  • C42T
  • C54T
  • C57T
  • T99C
  • C108A
  • T150A
  • C153T
  • T159C
  • G163A
  • C192T
  • C204T
  • A238G
  • G250A
  • T259C
  • C264T
  • C268A
  • C315T
Deletions
N/A
Insertions

seg1

ins_0:TCAAATATATTCAAT, ins_2280:TGTCGAATTGTTTAAAAACGA

seg2

ins_0:CAAACCATTTGA, ins_2274:TGAATTTAACTTGTCCTTCATGAAAAAATG

seg3

ins_0:TACTGATCCAAA, ins_2151:TTGTGGCAATGCTACTATTTGCTATCCATATTGTCCAAAAAAGTA

seg5

ins_0:GTAGATAATCACTCAATGAGTGACATCGAAGCC, ins_1497:AGAAAAATAC

seg6

ins_1425:A

seg7

ins_0:TAGATGTTTAAAG, ins_982:AAAACTA

seg8

ins_0:GTGACAAAAACATA

Amino acid substitutions

Substitutions called relative to the NC_026438.1, NC_026435.1, NC_026437.1, CY121680.1, NC_026436.1, MW626056.1, NC_026431.1 & NC_026432.1 references

Substitutions

HA1

  • HA1:K54Q
  • HA1:S74R
  • HA1:P83S
  • HA1:S84N
  • HA1:D97N
  • HA1:T120A
  • HA1:N129D
  • HA1:K130N
  • HA1:P137S
  • HA1:K142R
  • HA1:N156K
  • HA1:L161I
  • HA1:S162N
  • HA1:K163Q
  • HA1:S164T
  • HA1:S183P
  • HA1:S185I
  • HA1:A186T

HA2

  • HA2:E29D
  • HA2:I45V
  • HA2:E47K
  • HA2:I91V
  • HA2:S124H
  • HA2:I133T
  • HA2:E172K
  • HA2:E179D
  • HA2:V193A
  • HA2:V200I

M1

  • M1:L42I
  • M1:V80I
  • M1:K98R
  • M1:Q208K
  • M1:K230R

M2

  • M2:D21G
  • M2:S23N

NA

  • NA:I46V
  • NA:S52N
  • NA:S200N
  • NA:I264T
  • NA:S367L
  • NA:I396M
  • NA:V453M
  • NA:G454D
  • NA:K469N

NEP

  • NEP:D2E
  • NEP:N29S
  • NEP:T48A
  • NEP:M83I

NP

  • NP:E14D
  • NP:I33V
  • NP:V100I
  • NP:M105T
  • NP:X114E
  • NP:L122Q
  • NP:I136L
  • NP:V217I
  • NP:A336T
  • NP:N377S
  • NP:V425I
  • NP:S498N

NS1

  • NS1:D2E
  • NS1:E55K
  • NS1:T80A
  • NS1:V84I
  • NS1:S87P
  • NS1:L90I
  • NS1:I123V
  • NS1:E125D
  • NS1:K131E
  • NS1:A155T
  • NS1:N205S

PA

  • PA:V14I
  • PA:X18E
  • PA:I30V
  • PA:V63I
  • PA:V100I
  • PA:P224S
  • PA:S225C
  • PA:R262K
  • PA:N321K
  • PA:I330V
  • PA:A337T
  • PA:K339N
  • PA:R362K
  • PA:I438V
  • PA:I505V

PA-X

  • PA-X:V14I
  • PA-X:X18E
  • PA-X:I30V
  • PA-X:V63I
  • PA-X:V100I
  • PA-X:R199K
  • PA-X:N204S
  • PA-X:R206K
  • PA-X:R221Q
  • PA-X:L229S

PB1

  • PB1:G154D
  • PB1:V200I
  • PB1:K386R
  • PB1:I397M
  • PB1:I435T
  • PB1:K757R

PB2

  • PB2:R54K
  • PB2:M66I
  • PB2:T81M
  • PB2:D195N
  • PB2:G225S
  • PB2:R293K
  • PB2:R299K
  • PB2:V344M
  • PB2:I354L
  • PB2:S453T
  • PB2:L475M
  • PB2:T524A
  • PB2:V667I
  • PB2:V731I

SigPep

  • SigPep:I4V
  • SigPep:L8M
  • SigPep:A13T
Deletions
N/A
Insertions
N/A